| Eavesdropping on bacterial conversations may improve chronic wound healing
01/04/2010
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None
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| New compounds may control deadly fungal infections
12/22/2009
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None
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| Researchers discover new ways to treat chronic infections
12/18/2009
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| Alzheimer's research sheds light on potential treatments for urinary tract infections
11/24/2009
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| Tips from the Journals of the American Society for Microbiology
11/19/2009
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| Bacteria 'launch a shield' to resist attack
11/01/2009
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| Case Western Reserve awarded $1.57M for corneal infection research
10/07/2009
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| Forsyth receives highly competitive challenge grants
10/05/2009
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| Daily bathroom showers may deliver face full of pathogens, says CU-Boulder study
09/14/2009
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| Building better bone replacements with bacteria
09/06/2009
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| Autonomous underwater robot reduces ship fuel consumption
08/24/2009
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| UTSA biology researchers demystify elusive war zone bacterium
08/17/2009
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| Wood, Jayaraman receive NIH grant to combat biofilms
08/11/2009
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None
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| UTSA biologists win $940,000 in stimulus funds to advance research
07/31/2009
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None
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| 'Microfluidic palette' may paint clearer picture of biological processes
07/29/2009
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None
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| United we stand; divided we fall
07/14/2009
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| Microbial analysis, micropatterning methods featured in Cold Spring Harbor Protocols
07/01/2009
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None
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| New lab-on-a-chip measures mechanics of bacteria colonies
06/30/2009
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None
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| New mechanism fundamental to the spread of invasive yeast infections identified
06/15/2009
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| Cool plasma packs heat against biofilms
06/10/2009
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| New hull coatings for Navy ships cut fuel use, protect environment
06/04/2009
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| Texas A&M researchers examine 'invading' bacteria in DNA
06/02/2009
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None
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| Are you okay to kiss?
05/18/2009
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None
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| Bionic ears, bubbles, blast waves and biofilms
05/14/2009
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None
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| Thus the bile does not overflow
05/11/2009
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None
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| Two-pronged model could help foil tough cystic fibrosis infections
04/24/2009
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| Sugar on bacteria surface serves as base for a web of resistance
04/21/2009
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None
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| Genes that make bacteria make up their minds
03/29/2009
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None
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| Queen's scientists find new way to battle MRSA
03/25/2009
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None
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| Strategy discovered for fighting persistent bacterial infections
03/23/2009
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None
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| Syracuse University researchers build a new surface material that resists biofilm growth
03/19/2009
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None
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| No hiding place for infecting bacteria
03/15/2009
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None
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| Einstein researchers develop novel antibiotics that don't trigger resistance
03/13/2009
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None
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| Biofilms: Even stickier than suspected
03/12/2009
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None
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| New research reveals how cranberry products prevent urinary tract infections
03/09/2009
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None
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| Buckyballs could keep water systems flowing
03/05/2009
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none
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| Simple device can ensure food gets to the store bacteria free
03/02/2009
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| MIT, BU team combats antibiotic resistance with engineered viruses
03/02/2009
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None
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| Antibiotic resistance: A rising concern in marine ecosystems
02/13/2009
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None
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| New method monitors critical bacteria in wastewater treatment
02/04/2009
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None
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| Nanoemulsion potent against superbugs that kill cystic fibrosis patients
02/04/2009
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None
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| Single gene lets bacteria jump from host to host
02/01/2009
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None
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| E. coli persists against antibiotics through HipA-induced dormancy
01/15/2009
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None
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| USC dentist links Fosomax-type drugs to jaw necrosis
01/01/2009
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None
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| Three New Technologies Now Available for Licensing from MSU
12/18/2008
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None
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| Evolutionary Roots of Ancient Bacteria May Open New Line of Attack on CF
12/16/2008
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None
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| 'Zinc Zipper' Plays Key Role in Hospital-Acquired Infections
12/04/2008
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None
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| PNNL Researchers Earn Top Honors at Supercomputing Conference
12/03/2008
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None
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| Social Amoeba Seek Kin Association
11/25/2008
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None
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| Bacterial Biofilms as Fossil Makers
11/24/2008
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| Eastman Dental Center Awarded $1.6 million to Find Ways to Prevent Cavities
10/28/2008
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None
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| U of Chicago Scientists Invent Device that Controls, Measures Dynamics of Chemicals in Live Tissue
10/27/2008
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None
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| Collegiate Inventors Competition Recognizes Top Student Inventors
10/22/2008
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None
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| When Under Attack, Plants Can Signal Microbial Friends for Help
10/17/2008
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None
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| UC San Diego Bioengineers Fill Holes in Science of Cellular Self-Organization
10/06/2008
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None
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| 2008 Science and Engineering Visualization Challenge Winners Announced
09/26/2008
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None
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| Honey Effective in Killing Bacteria that Cause Chronic Sinusitis
09/23/2008
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| New Approach to Treating Cystic Fibrosis Lung Infection Shows Promise
09/22/2008
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| Bacteria's Sticky Glue is Clue to Vaccine Says Scientist
09/09/2008
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| Food Poisoning Bacteria Prefer Duck to Beef on Meat Factory Surfaces
09/09/2008
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| Milk May Help Bacteria Survive Against Low Levels of Antibiotics
09/07/2008
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| Living Sensor Can Warn of Arsenic Pollution
09/07/2008
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None
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| Rattlesnake-Type Poisons Used by Superbug Bacteria to Beat Our Defenses
09/07/2008
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None
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| MSU Biofilms Research Helps Set Standards for Everyday Products
08/22/2008
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None
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| OU Researchers Isolate Microorganisms that Convert Hydrocarbons to Natural Gas
08/19/2008
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None
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| Silver is the Key to Reducing Pneumonia Associated with Breathing Tubes
08/19/2008
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None
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| New Research Challenges Notion That Dinosaur Soft Tissues Still Survive
07/29/2008
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None
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| Biofilms Use Chemical Weapons
07/23/2008
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None
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| MSU Researcher Uses Grant to Study Little-Known but Largely Useful Microbes
07/22/2008
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None
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| New Chlorine-Tolerant, Desalination Membrane Hopes to Boost Access to Clean Water
07/22/2008
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| American Society for Microbiology Honors Marvin Whiteley
07/16/2008
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| Blue Light and Hydrogen Peroxide May Effectively Treat Biofilms That Cause Cavities and Gum Disease
06/21/2008
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| Microscopic "Clutch" Puts Flagellum in Neutral
06/19/2008
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| Chemical Engineering Researchers Identify Biofilms That Cause Infections
06/11/2008
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None
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| Source of Drug-Tolerant Tuberculosis Possibly Behind TB Relapses, Intensity of Treatment
06/11/2008
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None
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| Escalating Arms Race Between Virus and Host Pits Shuffling Viruses Against Microbial Silencers
05/22/2008
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None
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| American Chemical Society's Weekly PressPac
05/19/2008
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None
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| IADR and GlaxoSmithKline Consumer Healthcare Announce Winners
05/15/2008
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| Superbug Genome Sequenced
05/07/2008
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None
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| Bacterial Slime Helps Cause Serious Disease
05/04/2008
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None
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| Turning on Cell-Cell Communication Wipes Out Staph Biofilms
04/30/2008
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None
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| USC School of Dentistry Researchers Uncover Link Between Osteoporosis Drugs and Jaw Infection
04/29/2008
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None
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| Dr. Mom Was Right -- and Wrong -- about Washing Fruits and Vegetables
04/10/2008
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None
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| Veterinary College Researchers Explore Function of Biofilm in Bovine Respiratory Disease
04/03/2008
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None
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| Finely Tuned WspRs Help Bacteria Beat Body by Building Biofilm
03/24/2008
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None
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| Confronting the Challenge of Antimicrobial Resistance
03/10/2008
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None
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| MSU Professor's Research on Bacteria's Role in Precipitation Cycle Published by "Science"
02/29/2008
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None
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| Nature's Helpers: Using Microorganisms to Remove TCE from Water
02/28/2008
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None
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| Bacteria Beware: MIT Student Invents Knock-Out Punch for Antibiotic Resistance
02/27/2008
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None
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| New Study Finds Resistant Organisms at Core of Soft Contact Lens Corneal Infections
01/28/2008
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None
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| Life at the Jolt
01/03/2008
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None
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| Winemaking Waste Proves Effective Against Disease-Causing Bacteria in Early Studies
01/02/2008
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None
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| Bacteria that Cause Urinary Tract Infections Invade Bladder Cells
12/17/2007
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None
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| Microbial Fuel Cells Turn on the Juice
12/04/2007
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None
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| Liang Receives NIH Grant for Biofilm Research
11/30/2007
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None
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| Older Filters, Fresher Water
11/22/2007
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None
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| Princeton Scientists Break Cholera's Lines of Communication
11/14/2007
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| Together We Stand: Bacteria Organize to Survive Hostile Zones
11/13/2007
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None
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| Sound Medicine at Acoustics Meeting
11/13/2007
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none
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| Cranberry Sauce: Good for What Ails You
11/13/2007
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none
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| Microbial Biofilms Evoke Jekyll & Hyde Effects
10/26/2007
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none
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| Sticky Mussels Inspire Biomedical Engineer Yet Again
10/18/2007
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none
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| Appendix Isn't Useless at All: It's a Safe House for Bacteria
10/08/2007
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None
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| American Society for Microbiology Honors Lucas R. Hoffman
09/13/2007
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None
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| Organisms Found on Contact Lenses Can Provide Clues to Cause of Corneal Eye Infection
09/10/2007
|
Cultures of contact lenses may sometimes identify the organisms involved in cases of corneal eye infection, according to a report in the
September issue of Archives of Ophthalmology, one of the JAMA/Archives journals.
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| Banishing Biofilms: Loosening Their Grip Could Make Food Supply Safer
08/27/2007
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None
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| Mayo Clinic Researchers Discover New Diagnostic Test for Detecting Infection
08/15/2007
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None
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| Battling Biofilms Brings Together Academics and Industry at Conference
07/25/2007
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None
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MIT, BU Team Builds Viruses to Combat Harmful 'Biofilms' Work is step forward for synthetic biology
07/09/2007
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None
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| In Nature, Proteins Sweep Up Nanoparticles
06/14/2007
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None
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| Microbes at Work Cleaning up the Environment
06/14/2007
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None
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Community-Associated Staph Infections Involving Antibiotic-Resistant Bacteria Increase
05/28/2007
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None
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| WUSTL Creates Center to Study Women's Infectious Diseases
05/17/2007
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None
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| New Hope for Antibiotic Resistance
04/24/2007
|
A surprising new cell suicide theory developed at the University of Nebraska Medical Center, suggesting that some bacterial cells act as “suicide bombers,” could aid future research in developing drugs that can skirt the potentially catastrophic problem of bacterial resistance to antibiotics.
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Key Found to Kill Cystic Fibrosis Superbug
04/24/2007
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None
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| Research Explores Herbal Treatment for Recurring Urinary Tract Infections
04/08/2007
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None
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| UT Metroplex Institutions to Collaborate on Biomedical Research
04/04/2007
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None
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| Brush Anode and Tubular Cathode Scale Up Microbial Fuel Cells
03/21/2007
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None
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| Oral Biology Research Award Presented to Russell
03/21/2007
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None
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| UC Research Discovers New Way to Fight Antibiotic-Resistant Bacteria
03/15/2007
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None
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| JCI Table of Contents: March 15, 2007
03/15/2007
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None
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| Burroughs Wellcome Fund Awards $8.25 Million in Grants to Physician-Scientists
03/14/2007
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None
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| Mine Runoff Continues to Provide Clues to Microbial Diversification
03/07/2007
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None
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| Monochloramine Treatment Not as Effective in Protecting Drinking Water
03/01/2007
|
The results of what may be the most extensive comparison of two common disinfectants used by municipal water systems suggest that, from a security standpoint, traditional chlorination may be more effective than treatment with monochloramine.
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| Scientists Expand Microbe 'Gene Language'
03/01/2007
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None
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| Uniform Language for Describing Genes of Pathogenic and Beneficial Microbes
02/28/2007
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An international group of scientists has announced a major expansion of a lingua franca used to describe the activities of genes in living organisms. The expansion provides terms that scientists can use to describe the complex events that occur when a pathogenic or beneficial microbe encounters its host. Understanding these events is crucial for developing new interventions for preventing infections by disease-causing microbes while preserving or encouraging the presence of beneficial microbes. The unified language under development in this effort is called The Gene Ontology (GO). The new terms added to the GO will significantly bolster what is already a powerful tool for scientists to compare the functions of genes and proteins in a wide range of disease-related organisms. The ongoing initiative is part of the Plant-Associated Microbe Gene Ontology (PAMGO) project, a recently-established interest group of the worldwide Gene Ontology Consortium.
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| Magnetic Resonance Microscopy Research Lands Professor NSF Award
02/27/2007
|
A Montana State University professor has won a prestigious $400,000 Career Award from the National Science Foundation for her work in magnetic resonance microscopy, a technique that allows researchers to see the inner workings of devices as small as one-tenth of a millimeter in size.
Read More...
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| LLNL Researchers Review Bio Detection Technologies
02/27/2007
|
Researchers from Lawrence Livermore National Laboratory review several of the latest technologies in the most recent issue (Issue 3, 2007), of the British journal “The Analyst,
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| Swimming 'To the Left' Gets Bacteria Upstream, and May Promote Infection
02/26/2007
|
Yale engineers who study both flow hydrodynamics and how bacteria propel themselves report that one reason for the high incidence of infections associated with catheters in hospital patients may be that some pathogenic bacteria swim "to the left," in a study published in Physical Review Letters.
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| New Imaging Technique Tracks Traffic Patterns of White Blood Cells
02/26/2007
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None
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| Shotgun Sequencing Finds Nanoorganisms
12/21/2006
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None
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| Combination of Technologies Works Best Against E. coli
12/12/2006
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None
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| Snottites, Other Biofilms Hasten Cave Formation
12/11/2006
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None
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| Common Antacids Could Help Keep Gingivitis at Bay
11/02/2006
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None
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| Researchers Report Initial Success in Promising Approach to Prevent Tooth Decay
10/23/2006
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None
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| Diversity Promotes Cooperation Among Microbes
10/23/2006
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None
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| Research into Herpes Vaccine Among Seven New Biotechnologies Available for Licensing
10/06/2006
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None
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| Looking for New Approaches to Target Antibiotic-Resistant Bacteria
10/02/2006
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None
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| Foodborne Pathogens Hard to Remove from Produce, Research is Ongoing
10/02/2006
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None
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| Search on for Treatment of Slow-Healing Wounds
09/20/2006
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None
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| 'Crabby' Compound that Skewers Bacteria Could Prevent Medical Implant Infections
09/10/2006
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None
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| 'Conversation Stoppers' Fight Deadly Bacterial Infections
09/10/2006
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None
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| Wounds May One Day Heal Better, Faster, Due to New NIH-Funded Wound Healing Centers
09/06/2006
|
Diabetic ulcers. Gunshot wounds. Bedsores. The treatment of these and other wounds may improve, thanks to a new initiative of the National Institute of General Medical Sciences (NIGMS), a component of the National Institutes of Health (NIH).
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| Engineer Designs System to Put Wastewater to Work
08/07/2006
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None
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| The Midas Bug -- The Bacterial Alchemy of Gold
08/01/2006
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None
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| Purdue Creates New Low-Cost System to Detect Bacteria
07/27/2006
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None
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| Sandia Work Launched on Space Shuttle Shows Live Cells Influence Growth of Nanostructures
07/21/2006
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None
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| JCI Table of Contents: July 20, 2006
07/20/2006
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None
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| MSU Wins Millions to Find Treatments for Slow-Healing Wounds
07/19/2006
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None
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| Pitt Phage Hunter Takes on Tuberculosis
07/11/2006
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None
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| MSU Offers Four New Technologies for Licensing to Entrepreneurs
07/11/2006
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None
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| Chronic Middle Ear Infections Linked To Resistant Biofilm Bacteria
07/11/2006
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None
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| Problem: Implant Infection, Solution: Nanotech Surfaces
07/06/2006
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None
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| First Human Trial of Antibacterial Contact Lens
06/28/2006
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None
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| Cranberries Contain Possible Anti-Caries/Anti-Plaque Agents
06/28/2006
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None
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| Bacteria Can Protect Metal
06/20/2006
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None
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| Bacterium Takes a Shine to Metals
06/16/2006
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None
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| Research Highlights How Bacteria Produce Energy
05/22/2006
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None
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| Scientist Revs Up Power of Microbial Fuel Cells in Unexpected Ways
05/10/2006
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None
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| HAA Busters?
04/20/2006
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None
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| Tips from the Journals of the American Society for Microbiology
04/14/2006
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None
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| Fighting Fire with Fire
03/30/2006
|
University of Georgia scientists have found bacteria that kill listeria in processing plant floor drains, where the pathogen is known to settle and multiply.
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| New Method for Identifying Microbes
03/03/2006
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None
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| Study Suggests 'Noise' in Gene Expression Could Aid Bacterial Pathogenicity
02/15/2006
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None
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| Earth Rx: A Microbial Biotechnology Prescription for Global Environmental Health
02/15/2006
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None
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| Hot-Spring Bacteria Flip a Metabolic Switch
01/30/2006
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None
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| Common Food Preservative Might Provide Treatment for Cystic Fibrosis
01/26/2006
|
None
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| MRIs Better at Diagnosing Needs for 'Bionic Ear' Implants
01/11/2006
|
None
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| Scientists Find Ways to Crack Bacteria Barrier
12/20/2005
|
None
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| Pasteurizing Fruit? It Could Help Fight Salmonella
12/16/2005
|
None
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| Preventing Biofilms Could Help Fight TB
12/01/2005
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None
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| Antibacterial Coatings Cut Infection Rates
11/29/2005
|
None
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| Slimy Bacteria Leads to List of Discoveries
11/28/2005
|
None
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| UQ Researchers Turn Water into Watts
11/14/2005
|
None
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| Genes Involved in Biofilms
11/10/2005
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None
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| Say What? Bacterial Conversation Stoppers
09/29/2005
|
None
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| Solution to 'Legionella'
09/15/2005
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None
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| Hygienic Surfaces, Biocidal and Self-Cleaning Coatings
09/13/2005
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None
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| Scientists Determine Structure of Enzyme That Disrupts Bacterial Virulence
08/30/2005
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None
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| Applying Ecological Laws to Bacteria
08/02/2005
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None
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| MAP Helps Students Chart a Path to Science Careers
07/29/2005
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None
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| Microbes of Yellowstone Detailed in New Book by MSU Researcher
07/26/2005
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None
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| 9 Cases of Legionnaires' Disease Identified in New Rochelle
07/15/2005
|
None
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| Patented Device Creates Electricity and Treats Wastewater
07/07/2005
|
None
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| Endocarditis Infection Commonly Related to Health Care Factors, Increasingly Due to Staph
06/21/2005
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None
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| A Bacterial Printing Press that Regenerates Its Ink: Patterning Bacteria Using Soft Stamps
06/08/2005
|
105th General Meeting of the American Society for Microbiology
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| Raisins Fight Oral Bacteria
06/07/2005
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None
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| Identification of Bacteria in Water Biofilms
06/07/2005
|
105th General Meeting of the American Society for Microbiology
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| A New, Potentially Disease-Causing Bacterium Found in a Hot Tub
06/07/2005
|
105th General Meeting of the American Society for Microbiology
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| The Use of Bacteriophage for the Reduction of Catheter-Associated Infections
06/06/2005
|
105th General Meeting of the American Society for Microbiology
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| Microbial Corrosion of the USS Arizona
06/06/2005
|
105th General Meeting of the American Society for Microbiology
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| The Use of Bacteria to Strengthen Sand
06/06/2005
|
105th General Meeting of the American Society for Microbiology
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| Immune-System Cells May Promote Chronic Infections in Cystic Fibrosis
06/02/2005
|
None
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| Infection-Fighting Strategy Backfires in Cystic Fibrosis
06/02/2005
|
None
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| Innovative Coating Could Give Medical Implants a Longer Life
05/13/2005
|
Innovative Coating Could Give Medical Implants a Longer Life
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|
| Understanding How Bacteria Communicate May Help Scientists
05/12/2005
|
None
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| NIH Funds DOE Lab for Cellular Studies
05/11/2005
|
NIH Funds DOE Lab for Cellular Studies
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| Proteomics Brings Researchers Closer to Understanding Microbes that Produce Acid Mine Drainage
05/05/2005
|
None
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| Microbes Yield Secrets of Survival
05/05/2005
|
None
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| ORNL, UC Berkeley Unravel Real-World Clues to Earth's Mysteries
05/05/2005
|
ORNL, UC Berkeley Unravel Real-World Clues to Earth's Mysteries
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| Oral Bacteria May Predict Pregnancy Outcomes
03/30/2005
|
none
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| Urine Helps Infectious Yeast Stick
03/29/2005
|
none
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| Using Molecular Technique, Researcher Identify Hospital Pool Bacterial Pathogen
03/14/2005
|
None
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|
| Newly Patented System Fights Corrosion
03/14/2005
|
None
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|
| To Control Germs, Scientists Deploy Tiny Agents Provocateurs
03/13/2005
|
none
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| Sequencing of Marine Bacterium will help Study of Cell Communication
02/07/2005
|
none
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| PGA on a Tour Under the Skin
02/03/2005
|
none
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| Substance Protects Resilient Staph Bacteria
02/03/2005
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none
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| Systems Microbiology has Great Scientific Promise in Health and Environment
01/06/2005
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None
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| A Prognostic Marker for Outcome in Ventilator-Associated Pneumonia
01/03/2005
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A Prognostic Marker for Outcome in Ventilator-Associated Pneumonia
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| Journal of Dental Research: New Editor, New Content, New Look, New Access
12/21/2004
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None
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| Study by US, Hebrew University Scientists Sheds Light on how Bacteria Persist Despite Antibiotics
12/09/2004
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none
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| NIDCR Launches Unique Initiative On Oral Biofilm
12/07/2004
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none
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| New Weapon In Germ Warfare: 'Jamming' Bacteria Signals Stops Cholera
12/07/2004
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none
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| New Study Discovers Why “Persister” Cells Never Say Die
12/04/2004
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none
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| UCSB Researchers Advance Understanding of Urinary Tract Infections
11/22/2004
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none
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| Diamonds are a Urologist's Best Friend
11/18/2004
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none
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| Community Living Causes Bacteria To Diversify
11/15/2004
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none
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| Research with Red Tide Toxin Yields Potential Therapies for Cystic Fibrosis
11/12/2004
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none
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| Bug's-Eye-View of Urinary Tract Reveals E.coli Infection Genes
10/25/2004
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None
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| New Method Studies Living Bacteria Cells
10/22/2004
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None
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| OHSU Study: Bacterial Switching Mechanism Key to Survival
10/21/2004
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None
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| UF Scientists Have Bionanotechnology Recipe To Find Elusive Bacteria
10/11/2004
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none
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| The Language of Bacteria... and Just About Everything Else
09/13/2004
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none
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| UV Light, Coatings Reduce Bacterial Adhesion up to 50 Percent
08/26/2004
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None
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| How Bacteria Fight Antibiotics
08/13/2004
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none
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| Debaffling Biofilms
08/06/2004
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None
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| Shower Curtains May Harbor Harmful Microbes
07/15/2004
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None
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| Finding the Hole in the Defenses of Cavity-Creating Microbes
06/25/2004
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None
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| Researchers Recommend New Approach to Combat Drug-Resistant Staph Infections
06/24/2004
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None
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| National Science Foundation awards MSU student $121,500
04/19/2004
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National Science Foundation awards MSU student $121,500
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| Decoding a Sulfate-Breathing Bug
04/13/2004
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Decoding a Sulfate-Breathing Bug
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| The American Academy of Microbiology Releases Report
04/07/2004
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The Global Genome Question: Microbes as the Key to Understanding Evolution and Ecology
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| Molasses and Whey Mix with Mine Tailings
04/07/2004
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Molasses and Whey Mix with Mine Tailings
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| Defence Work Sheds Light on Hospital Bacteria
04/06/2004
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Defence work sheds light on hospital bacteria
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| Research on Cholera Bacteria Focuses on Biofilm Formation
03/04/2004
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Not Available
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| Biohazard Lurks in Bathrooms
02/16/2004
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Shower curtains awash with potentially harmful bacteria
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| Mouth Microbes May Help Shape Immune System, Says Stanford Research Team
02/16/2004
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Mouth Microbes May Help Shape Immune System, Says Stanford Research Team
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| It's a Stirring Tale of Bacteria
02/10/2004
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It's a Stirring Tale of Bacteria
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| Eastman Kodak Donates Inventions to MSU
02/05/2004
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http://www.montana.edu/commserv/csnews/nwview.php?article=1482
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| Pink Slime Yields First Set of Genomes Sequenced from Environment
02/04/2004
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Pink slime yields first set of genomes sequenced from environment
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| Microbial Biofilm Yields Community Genomes, Metabolic Clues
02/01/2004
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Microbial biofilm yields community genomes, metabolic clues
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| Understanding Urinary Tract Infections
01/19/2004
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Scientists film bacteria changing, collaborating to defeat bladder cell defenses
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| DOWN in the MOUTH SCSU Professor Studies Biofilms that Coat the Teeth
01/18/2004
|
Down in the Mouth
by Abram Katz , Register Science Editor
01/18/2004
Copyright 2004 New Haven Register - Reprinted with permission
www.newhavenregister.com
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| The Search for Answers
12/10/2003
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The Search for Answers
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| Bacteria--109 Tough Cookies
12/01/2003
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None
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| Microbial Multicellularity
12/01/2003
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Many species of bacteria live in a social, coordinated fashion, and they'll even die to keep it that way.
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| Restoring Voices
12/01/2003
|
The voice is one of the most distinctive features of an individual, conveying much more than words alone; it also gives clues about age, sex and emotions. But after a laryngectomy, patients may be left with only a deep, gravelly rasp or nothing more than a toneless whisper. Now, with inspiration from a range of ordinary objects, Dutch researchers are developing prosthetic voice-producing devices to help laryngectomy patients regain a more normal sound and a better quality of life.
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| Glucans Mediate Biofilm Resistance
11/20/2003
|
Some microorganisms have the ability to form a microbial community that attaches to surfaces and is generally referred to as a biofilm. These films are highly resistant to antibiotics, on the order of 10–1000 times, making them hard to control and dangerous in medical settings. But despite this importance, the mechanisms behind biofilm resistance have been unclear. In the November 20 Nature, Thien-Fah Mah and colleagues at Dartmouth Medical School have identified a genetic component of biofilm resistance in the pathogen Pseudomonas aeruginosa (Nature, 426:306-310, November 20, 2003).
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| MSU Slimy Bacteria Study Appears in Major Journal
11/20/2003
|
MSU scientists Betsey Pitts and Phil Stewart are coauthors on a paper on bacterial resistance to antibiotics published in the Nov. 20 issue of the prestigious journal Nature. (MSU photo by Stephen Hunts)
Antibiotics don't work against bacteria stuck together in tight-knit communities called biofilms. That much scientists knew.
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| Biofilm Antibiotic Resistance May Be Susceptible to Genetic Approach
11/19/2003
|
Biofilms, slimy clusters of bacteria that are resistant to antibiotics, may have a genetic chink in their armor that could be exploited to combat the infections they cause. A study led by Dartmouth Medical School (DMS) researchers used a genetic-based approach to begin to understand how biofilms can withstand antibacterial treatments.
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| Cholera Biofilm Dynamics
11/05/2003
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The O139 O-antigen and Ca2+ are essential for Vibrio cholerae biofilm development
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| Improving the Quality of Life for Larynx Cancer Patients
10/21/2003
|
Currently, voice
rehabilitation of larynx cancer patients is performed by inserting a
one-way shunt valve between trachea and oesophagus that prevents food
and liquid from entering the trachea. Pressing the tracheal opening
with a finger forces exhaled air through the shunt valve to the
oesophagus, where soft tissue structures serve as a substitute voice.
However, the voice is in many cases of poor quality and the process
creates a mental barrier during speaking, as patients have to
literally point at their handicap.
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| The American Academy of Microbiology Releases Report
09/22/2003
|
Microbial Communities: From Life Apart to Life Together
The size of microbes belies their impact across the globe, especially when they are grouped together in microbial communities. Microbial communities have significant effects upon virtually all aspects of human and environmental health, from films inside household water pipes, to the vast communities in the oceans that process global cycling of nutrients, to the increasingly important problem of antibiotic resistance.
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| Tips from the Journals of the American Society for Microbiology
09/11/2003
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Ingredient in Domestic Detergent May Not Contribute to Antibiotic Resistance
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| Bacterial Biofilms May Be Source of Recurrent Tonsillitis
09/02/2003
|
Recurring tonsil infections and sore throats are a fact of life for many children. The pediatrician prescribes antibiotics, and they help for a while, but the infection returns. The pattern repeats itself until the doctor — or the frustrated parents — finally decide that the wrinkly olive-sized ovals of inflamed tonsil tissue must come out. Why, they wonder, can't the body eliminate these infections, even with the help of antibiotics?
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| Social Mobility: Study Shows Bacteria Seek Each Other Out
07/28/2003
|
Findings could suggest new ways of attacking harmful bacteria
It turns out that bacteria are
real social climbers. Or at least social wigglers.
A study by Princeton University
scientists has shown that bacteria actively move around their
environments to form social organizations. The researchers placed
bacteria in minute mazes and found that they sought each other out
using chemical signals.
Biologists have become
increasingly aware of social interactions among bacteria, but
previously believed that clusters formed only when bacteria randomly
landed somewhere, then multiplied into dense populations. The
discovery that they actively move into gatherings underscores the
importance of bacterial interactions and could eventually lead to new
drugs that disrupt the congregating behavior of harmful germs, said
Jeffry Stock, a professor of molecular biology and coauthor of the
paper.
"It makes sense, but it's
surprising that it's as pervasive as it now seems to be," said Stock.
The researchers observed the
gathering behavior in E. coli as well as in V. harveyi,
a marine bacteria that glows when it achieves a high-density
population. They found that when placed in mazes the bacteria
congregated in small rooms and dead-end pathways. Once clustered, the
V. harveyi turned on the genes that make them glow.
Biologists had previously
believed that bacteria's ability to move and follow chemical signals
-- a process called chemotaxis -- was primarily a means of dispersing
and seeking food. The new study, published in the July 11 issue of
Science, shows that chemotaxis may also be important for facilitating
cooperative behavior.
The work was collaboration
between Stock's lab in biology and that of Robert Austin, a professor
of physics. Emil Yuzbashyan, a graduate student in Austin's lab
noticed unusual clumping when he put E. coli into
microscopically small mazes made of silicone. Biologists in Stock's
lab supplied mutant strains of bacteria that lacked genes necessary
for sensing chemical signals and chemotaxis. They found that bacteria
themselves emit a key chemical attractant and that those lacking the
gene for the receptor that senses that attractant did not cluster as
normal bacteria did.
Disrupting chemotaxis could be a
route to attacking biofilms, a common type of bacterial interaction in
which they form a colony that is resistant to antibiotic drugs and
chemicals, the researchers said. Biofilms pose a common danger to
patients receiving medical implants and cause trouble for ships that
develop biofilms on their hulls.
Clustering also allows bacteria
to perform a coordinated activity called quorum sensing in which they
turn on certain genes only when they sense that they are part of a
dense population. Some disease-causing bacteria are believed to rely
on quorum sensing in mounting a successful infection. The V.
harveyi in the experiment glowed as a result of quorum sensing
after they gathered into a dense population.
"Our paper points out that you
don't necessarily need growth to achieve quorum sensing," said Peter
Wolanin, a postdoctoral researcher in Stock's lab. "The bacteria can
actively seek each other out to engage in collective social behavior."
The behavior observed in the
experiment also may have been a survival mechanism, said Sungsu Park,
a postdoctoral researcher in Austin's lab and first author of the
paper. The research was conducted with the bacteria in a
nutrient-depleted environment that resembles the natural conditions
for bacteria much of the time. "The bacteria are chasing amino acids
released from their own cell bodies during starvation conditions,"
said Park. "So by getting close to each other they have a better
chance of getting nutrients."
The researchers also have
developed a mathematical model that simulates the bacterial
congregation, said Park. They plan further research to investigate the
relation between bacterial behavior and the size and geometry of their
physical environment.
###
Additional work on the study was done by Pascal Silberzan, a
former member of the Princeton physics department and now a researcher
at the Curie Institute in Paris.
###
Public Release Date: 28 July 2003
Contact: Steven Schultz
sschultz@princeton.edu
609-258-5729
Princeton University
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| Germs Throw Cold Water on Hot Tub Hygiene
07/21/2003
|
Cue the ''Psycho'' music.
There's a stranger in your shower, though it's not a knife-wielding
murderer. It's a mysterious consortium of bacteria embedded in shower
curtain slime. They also hover in the mist above hot tubs and swim
with you in pools. Before you ease onto those pulsating jets of water
to soothe your aches and pains, consider that the bacteria in indoor
hot tubs, pools, and even decorative fountains and waterfalls may pose
a health risk.
The Centers for Disease Control
and Prevention in Atlanta has tracked respiratory infections
associated with hot tubs and pool use for some time. Recent reports
from the Mayo Clinic and the National Jewish Medical and Research
Center describe how formerly healthy patients who used indoor hot tubs
had developed a productive cough, fever and fatigue, and eventually
needed lung biopsies, respirators, intravenous antibiotics and
steroids in an attempt to treat their illness. If patients continued
using their hot tubs, their conditions worsened. Baffled doctors
consulted the research centers, which recommended removing the hot
tubs. After the hot tubs were removed, the patients recovered from
what the researchers termed ''hot tub lung.''
Technically, hot tub lung covers
several conditions, including pneumonia and a hypersensitivity
reaction that is not actually an infection. Researchers attribute hot
tub lung to bacteria that thrive in the slime on pipes and other wet
surfaces. This slime forms as bacteria settle on a surface and begin
to secrete a gluey, adhesive substance. That bacteria-laden slime,
which is known as a biofilm, forms in the pipes and filters of hot
tubs. The tub's powerful jets force some of the biofilm free, and tiny
biofilm flakes bubble to the surface and aerosolize into the mist,
which people soaking in the tub inhale.
Some of the bacteria that thrive
in biofilms belong to the mycobacteria family, which are common in
soil and water. Most mycobacteria are harmless, but some cause
tuberculosis and leprosy. Others are ''MACs,'' or mycobacterium avium
complex, which cause a pulmonary infection that looks like
tuberculosis, but is not as dangerous and is not contagious. According
to microbiologist Norman Pace of the University of Colorado, MAC
infections commonly appear in elderly women who like to garden: ''I
suspect they stir up the soil mycobacterium that usually don't harm
us, but because their immune systems are weaker with age, they are
getting sick.''
Another bacterium that can grow
in biofilms is Legionella, the culprit behind the outbreak of
Legionnaires' disease during a Philadelphia hotel convention some
years ago. Legionella normally inhabit the algae film on ponds, but
they also occupy the biofilms in air conditioning condensers and
hot-water systems. Bill Costerton, a biofilm researcher at Montana
State University at Bozeman, said he believes such outbreaks are just
the tip of the iceberg; untold millions have inhaled similar biofilm
flakes over the years. While those biofilms set up long-term lodging
in our lungs, a healthy immune system can keep the bacteria in check.
But if we become stressed, ill or old, we may succumb to some
hard-to-diagnose respiratory infection that will never be traced to an
air-conditioned room or a hot tub we visited in our youth.
Researchers stress the need for
more studies to determine the nature of these bacterial biofilms and
their risks to both immune-compromised and healthy people. Studies on
hot tubs in hospitals and other therapeutic facilities will be
controversial, according to Pace, because they may show that people
are getting sick from facilities they are visiting for their health.
And yet, Pace said, there is not much more those facilities can do
currently to protect their visitors. Most already follow rigorous
hygiene standards, but their best efforts still may not be sufficient.
Biofilms can persist through disinfection because their slime protects
the bacteria from chemicals. Likewise, many bacteria actually thrive
in hot water, while the heat reduces the effectiveness of
disinfectants. Scientists are developing ways to prevent biofilms from
accumulating, but so far, slime has the upper hand.
Several years ago, researchers
also isolated tiny amounts of MAC bacteria from the scum on shower
curtains. While shower-curtain MACs pose little risk to us because
they rarely aerosolize, some researchers hypothesize that they may be
the source of pneumonias that late-stage AIDS patients often contract.
After reading about MACs in
shower curtain scum, Pace became curious about what else was in there.
He found that about 45 percent of the bacteria belong to the
sphingomonas species, which are well-known slime producers. He was
surprised to find that another 45 percent are methanobacteria, which
eat methane and break down components in plastic and other materials.
These methane lovers are probably not dangerous, but they may nurture
both slime-producing bacteria and disease-causing stowaways. Pace
surmised that the slime producers somehow depend on the methane
lovers. In turn, the slime provides a safe haven for a few MACs and
other potentially harmful bacteria.
Ultimately, finding ways to
prevent slime could be hot tub lung's last gasp. Meanwhile, we need to
drain our hot tubs, dry out the biofilms, disinfect the pipes and
filters, and scrub, scrub, scrub. If you should come down with an
unexplained respiratory infection, researchers recommend discussing
your use of indoor hot tubs and pools with your doctor.
There's still a lot to learn
about everyday hygiene and the microbes we want to subdue. ''This
research illustrates,'' Pace said, ''that the unknown character of the
microbial world is not only all around us, but we are literally
immersed in it.''
This story ran on page B13 of the Boston Globe on 5/6/2003.
###
Published with permission: 21 July 2003
Contact: Cathryn M. Delude
Globe Correspondent
The Writing Company
http://www.thewritingco.com
Cathryn@thewritingco.com
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|
| An Aspirin a Day Keeps Staphylococcus aureus Away
07/15/2003
|
In the July 15 issue of The
Journal of Clinical Investigation, Ambrose Cheung and colleagues at
Dartmouth School of Medicine in New Hampshire, USA, report that
salicylic acid (SAL), the major metabolite of aspirin, downregulates
two Staphylococcus aureus genes key to this organism's
pathogenesis.
Over 100 years have passed since
S. aureus was first described as the organism responsible for
causing sepsis and abscesses. Today it remains a leading cause of
serious infections such as endocarditis, pneumonia, and septicemia and
requires intensive antibiotic therapy, which is often unsuccessful due
to the rise of antibiotic resistant strains.
Aspirin has previously been shown
to reduce the virulence of S. aureus in models of endocarditis.
In an earlier study, this same group found that while administration
of aspirin or its metabolite, SAL, was capable of reducing the ability
of S. aureus to attach to host cells, the effect was
significantly enhanced following SAL administration.
In this issue of the JCI, Cheung
and colleagues extend these earlier findings and report that treatment
with SAL induced activation of the S. aureus stress response
gene sigB, resulting in downregulation of regulons sarA and agr, which
control the expression of the genes encoding a-hemolysin and
fibronectin. This downregulation resulted in decreased ability of the
bacteria to adhere to host cells, and reduced S. aureus
toxin-mediated hemolysis and thrombolysis of host cells.
"The establishing of a
straightforward, unequivocal strategy to downregulate staphylococcal
virulence using a cheap, simple, relatively non-toxic, resorbable
compound such as SAL may be seen as major progress in the development
of intervening strategies in addition to antimicrobial drugs" stated
Professor Mathias Herrmann, Director of the Department of Bacteriology
and Hygiene at the University of Saarland, Germany in his accompanying
commentary. The report is the first description of aspirin-mediated
genetic effects against S. aureus and represents an exciting
new prospect for this widely used and established drug.
###
TITLE: Salicylic acid attenuates virulence in endovascular infections
by targeting global regulatory pathways in Staphylococcus aureus
AUTHOR CONTACT:
Ambrose L. Cheung
Dartmouth Medical School, Hanover, New Hampshire, USA.
Phone: 603-650-1310
Fax: 603-650-1362
Email: ambrose.cheung@dartmouth.edu
View the PDF of this article at:
https://www.the-jci.org/press/16876.pdf
ACCOMPANYING COMMENTARY:
Salicylic acid: an old dog, new tricks, and staphylococcal
disease
AUTHOR CONTACT:
Mathias Herrmann
University of Saarland Hospital, Homburg/Saar, Germany.
Phone: 49-6841-162-3900
Fax: 49-6841-162-3985
Email: mathias.herrmann@uniklinik-saarland.de
View the PDF of this commentary at:
https://www.the-jci.org/press/19143.pdf
###
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|
| Researchers Envision Intelligent Implants
07/08/2003
|
Imagine a replacement hip or
knee that was intelligent enough to recognize if it was infected,
diagnose and treat the infection and report back to the doctor what it
had done. Well it may not be a reality yet, but researchers today
announced the development of an interdisciplinary group of scientists
that hopes to design and build such a device.
"Two to three percent of total
joint replacements fail due to chronic
bacterial biofilm infections. The only recourse for such patients is
the traumatic removal of the implant which results in additional bone
loss, extensive soft tissue destruction, months of forced bed rest
with intravenous antibiotics and significant loss of quality of life
due to complete loss of mobility, " says Garth Ehrlich of the Center
for Genomic Sciences at the Allegheny Singer Research Institute in
Pittsburgh, one of the organizers of the working group. Ehrlich
presented the group's vision at the American Society for
Microbiology's Conference on Bio- Micro- and Nanosystems.
Ehrlich and his colleagues
envision an intelligent implant covered in microelectronic mechanical
systems (MEMs)-based biosensors that could detect these debilitating
infections early and identify the bacteria responsible. The implant
would then provide therapy by dispensing the appropriate antibacterial
compound from an internal reservoir and monitor the effectiveness of
the treatment. In addition, the implant would be able to communicate
what it had done back to a physician using wireless technology.
The group, which met for the
first time in April, includes a variety of
specialities that do not normally work together including clinicians,
microbiologists, electrical engineers, biofilms experts and MEMs
technologists. Because of the diverse backgrounds, they spent much of
meeting giving lectures about their respective fields. "Everyone was
trying to educate everyone else," says Ehrlich. Ehrlich cautions that
this is a long-term project and there are no guarantees. He estimates
a minimum of seven years before they even have a prototype.
"There are technical hurdles that
still need to be overcome but I'm
fairly confident that technology is evolving rapidly enough that we
will be able to do this," says Ehrlich. "The ever increasing number of
total joint replacements being performed on an aging U.S. population
mark this disease a high priority for the development of new
interventional strategies."
###
The ASM Conference on Bio-, Micro-, Nanosystems, held in
collaboration with the IEEE Engineering in Medicine and Biology
Society on July 7-10, 2003 at the Plaza Hotel in New York City, is
intended to provide an interdisciplinary forum for microbiologists and
engineers to explore ways in which microbiology can contribute to the
growing field of nanotechnology. For further information on the
meeting contact Jim Sliwa, ASM Office of Communications.
###
Public Release Date: 8 July 2003
Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology
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|
| Biofilms Inside Bladder Cells May Cause Recurrent Urinary Tract Infections
07/01/2003
|
Bacteria that invade bladder cells and grow into structured colonies known as biofilms may be responsible for many recurrent urinary tract infections (UTIs), according to researchers at Washington University School of Medicine in St. Louis.
Read More...
|
| Biofilms in Cystic Fibrosis
06/10/2003
|
Analysis of Pseudomonas extracellular matrix sheds light on chronic lung infections by Andrea Rinaldi
The Scientist 10 Jun 2003 Linked 06/10/03
Free registration required

Read More...
|
| Few Microbiological Differences in Households Using Antibacterials
05/21/2003
|
A microbiological survey of households finds little significant difference in levels of bacteria or antibiotic resistance between those that use antibacterial cleaning products and those who do not. Researchers from Tufts University School of Medicine report their findings today at the 103rd General Meeting of the American Society for Microbiology.
Read More...
|
| Pathogenic Yeasts and Fungi: A Growing Health Concern
05/13/2003
|
Like weeds in a lawn, pathogenic fungi and yeasts (single-celled fungi) can invade and overtake our bodies. In people with healthy immune systems, cells called macrophages and neutrophils engulf these pathogens, nipping them in the bud. But when the immune system is weakened by disease or drugs, fungi – much like weeds in your garden – can grow unchecked.
Read More...
|
| War on Germs Gets Cutting-Edge Weapon from Ancient World Technique
05/09/2003
|
Antimicrobial powder coating for hospitals, homes uses silver -- Germ fighter pioneered by Egyptians, Phoenicians
Read More...
|
| Breakthrough in Fight Against Infection Misery
05/07/2003
|
Scientists at Cardiff University, UK, have made a breakthrough in a 30-year battle to solve a medical problem, which causes pain and misery for millions of people around the world, and costs health services many millions of dollars.
Read More...
|
| Team Jams Bacteria Talk to Boost Bio-Product Yields
05/05/2003
|
In studies that could be vital to an expanding field of industrial biotechnology, scientists at the Center for Biosystems Research are learning to censor what E. coli bacteria are 'talking' about.
Read More...
|
| Microbes Related to Infant Lung Infections Reduced by Two-Thirds Using Specialized Ventilation System Device in ICU
05/03/2003
|
Pediatric researchers at Women and Children's Hospital here have shown that the incidence of disease-producing microorganisms in the lungs of its infants on life support can be reduced markedly by installing an ultraviolet germicidal irradiation device in the ventilation system of its neonatal intensive care unit.
Read More...
|
| Borrowing from Ebola Virus Could Aid Cystic Fibrosis Gene Therapy
04/30/2003
|
A problem with current efforts in developing a cystic fibrosis gene therapy is that delivering genes into airway cells is inefficient and requires disrupting the integrity of the cell layer. However, a finding by University of Iowa researchers and colleagues may help solve the problem by using a surprising tool -- a modified piece of the Ebola virus.
Read More...
|
| Cystic Fibrosis Gene Therapy Trial Results Encouraging
04/29/2003
|
Scientists and physicians in Cleveland have announced encouraging results from the first-of-its-kind gene therapy trial involving cystic fibrosis (CF) patients and a new compacted DNA technology.
Read More...
|
| Small Talk--The Gabfest of Microbial Communication
04/29/2003
|
ONR-Sponsored Bonnie Bassler Looks at Bacterial Communication
Read More...
|
| Compound Developed from Mussels May Lead to Safer, More Effective Medical Implants
04/07/2003
|
Medical implants may soon get better at preventing life-threatening clogs and bacterial infections thanks to an unusual coating that is being developed from mussels, according to researchers at Northwestern University.
Read More...
|
| Hospital-Acquired Infections at the 11th ECCMID in Istanbul: It Was the Tea Flask that Spread the Germs!
04/06/2003
|
Hospital-acquired infections, or "nosocomial" infections in medical jargon, are a continual worry for specialists. They are becoming more and more common, and represent an ever-increasing economic burden, costing the UK alone over a billion pounds sterling every year.
Read More...
|
| Barnacles Will Cling No More with Self-Cleaning, Non-Toxic Coating for Ships Developed by Cornell Researchers
03/27/2003
|
A research group at Cornell University, Ithaca, N.Y., led by Christopher Ober, has developed two types of non-toxic paint, one hydrophilic and one hydrophobic, that effectively prevent fouling, whether by bacteria or barnacles.
Read More...
|
| New Proteomic Techniques Reveal Workings of Bacteria Linked to Cystic Fibrosis
03/26/2003
|
Research utilized quantitative proteomic analysis using mass spectrometry
Read More...
|
| A Closer Look Yields New Clues to Why Bacteria Stick to Things
03/25/2003
|
A bacterium's ability to change its hairstyle may help in the effort to clean contaminated groundwater for drinking, according to Penn State researchers.
Read More...
|
| Visionary German Wins 2003 Stockholm Water Prize
03/23/2003
|
The German Professor Peter A. Wilderer, who has promoted and developed holistic, interdisciplinary research for more than 30 years in the pursuit of sustainable water use and sanitation, was announced today as the 2003 Stockholm Water Prize Laureate.
Read More...
|
| Biofilms Journal: Announcement and Call for Papers
03/06/2003
|
Cambridge University Press are delighted to announce the launch of Biofilms. Scheduled for first publication early in 2004, this new interdisciplinary journal is being launched in response to the need to provide a forum exclusively devoted to research involving biofilms.
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| Researchers Design System to Improve Disinfection of Water Used in Food Processing
02/26/2003
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Georgia Institute of Technology researchers have developed a better-performing, less costly method of disinfecting water used in food processing.
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| Out of Agonists Comes an Antagonist
02/10/2003
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The Scientist 10 Feb 2003 Linked with permission, 02/17/03
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| Orthopaedic Researchers Honored
02/05/2003
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The 2003 Kappa Delta Sorority and Orthopaedic Research and Education Foundation (OREF) research awards were presented today during the Opening Ceremonies of the 70th Annual Meeting of the American Academy of Orthopaedic Surgeons in New Orleans.
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| New Drug Lead Fights Bacteria that can be Lethal by Disrupting Quorum Sensing and Biofilms
01/24/2003
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Compound could lead to a new generation of antibiotics that battle resistance
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| Two New MSU-Developed Technologies Available for Licensing
01/09/2003
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A naturally occurring organism that protects sugarbeets from disease and a manual for studying clumps of bacteria called biofilms are two new technologies developed at Montana State University-Bozeman.
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| Surface Treatments Could Make Ready-To-Eat Products Safer
12/18/2002
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A new product called acidified calcium sulfate is showing promise as a way to kill Listeria monocytogenes and keep lunch meats and frankfurters safer for consumers.
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| Bacteria Can't Do Their Thing If They Don't Have Cling
11/14/2002
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Scientists open door to possible new treatments for urinary tract infections
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| Mayo Clinic Physicians Look for Cause of 'Hot Tub Lung'
11/12/2002
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Mayo Clinic researchers in the November issue of Mayo Clinic Proceedings present two cases and offer their conclusions as to the cause of the patients' lung inflammation.
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| Philips and Scientific American Magazine Announce First-Ever Special Issue on Oral Health
11/07/2002
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Continuing its commitment to bringing the latest scientific news to the dental professional community and their patients, the Oral Healthcare division of Philips Electronics has partnered with Scientific American, the nation's premier science and technology magazine, to produce the magazine's first-ever special issue devoted to oral health.
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| Dispersin' Escherichia coli all over the gut
11/05/2002
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James Nataro and colleagues of the University of Maryland School of Medicine were searching for proteins that contribute to EAEC's success as a human pathogen as well as those that provoke a robust immune response and might serve as vaccines.
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| Cipro, Related Antibiotics Over-Prescribed, Fueling Microbe Resistance
09/28/2002
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A new study heightens concerns that Cipro and related broad-spectrum antibiotics known as fluoroquinolones are being over-prescribed, accelerating bacterial resistance to the drugs and reducing their ability to treat infections.
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| American Society for Microbiology Journals Tipsheet: September 2002
09/18/2002
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Egg Yolk a Possible Alternative to Antibiotic Treatment of Ulcers, Bacteria Work with Diet in Heart Disease, Chewing Tobacco Contaminated with Bacteria
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| New Antibacterial Coating May Prolong Contact Lens Life
08/22/2002
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The hassle of removing and cleaning your contacts every night, or even every month, could become a thing of the past, based on a study involving a new contact lens coating that kills bacteria.
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| Ulcer-causing Bacteria Use Stomach Inflammation to Their Advantage
07/25/2002
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The bacterium that causes stomach inflammation (gastritis), peptic ulcers and gastric cancer thrives in the human stomach by triggering changes in stomach cells and using those changes to its own advantage, say researchers in Sweden and at Washington University School of Medicine in St. Louis.
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| Souped-Up Bacteria Fight Tooth Decay
07/10/2002
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A bacterium found in many dairy products has been altered to fight against dental caries. The July issue of Nature Biotechnology reports a study in which beneficial bacterium Lactobacillus zeae is engineered to produce an antibody on its surface that neutralizes the detrimental streptococcal bacteria that cause tooth decay.
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| Surprising Role for Staph’s Toxic Shock Toxin
07/08/2002
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NYU School of Medicine scientists have discovered a novel role for the toxin that is responsible for toxic shock syndrome, a deadly infection linked to the use of highly absorbent tampons.
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| Fluid Forces Within the Body Help Invasive Bacteria
06/27/2002
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Researchers at the University of Washington have learned that something most people take for granted is not true: that the force of fluids within the human body helps to break the adhesive bonds of invasive bacteria and counterbalance infection.
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| Structure of Key Protein that Enables Quorum-Sensing Bacteria to Communicate and Spread Infection is Solved by Research Team
06/26/2002
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A decade after microbiologists began to suspect that many groups of bacteria can communicate -- by releasing and detecting chemical pheromones to gauge their population density -- the molecular structure of a key protein in this interbacterial communication has been solved.
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| New Device Removes Drinking Water Contaminants
06/13/2002
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A Northwestern University environmental engineer has received a U.S. patent for a treatment device that renders perchlorate - a thyroid-damaging ingredient of rocket fuel and a drinking water problem - harmless. The applications extend beyond the safety of drinking water and this one pollutant.
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| Culprit in Ear Infections is a 'Biofilm' that Protects Bacteria
06/04/2002
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Parents whose children have recurrent ear infections often feel they spoon gallons of antibiotics into their children, only to hear a troubling diagnosis from the doctor: Yes, the drugs cured the infection, but there's still fluid in the ear. Now, scientists think that remaining fluid might be even more menacing.
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| Study of Aquatic Mussels Indicates They May Yield New Antifouling Materials, Surgical Adhesives
06/04/2002
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New insights into how aquatic mussels bind tightly to rocks and other surfaces could lead to surgical applications and improved adhesives, it was reported today at the Great Lakes Regional meeting of the American Chemical Society, the world's largest scientific society.
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| A Defense Mechanism Against Biofilm Infections Identified
05/30/2002
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Findings from University of Iowa investigators shed light on how the body normally prevents biofilm development.
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| Sweat and Tears Drive Bugs Apart
05/30/2002
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Natural antibacterial stops bugs finding strength in numbers
Nature 30 May 2002 Linked with permission, 06/05/02
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| DNA Testing Identifies Suspect Bacteria in Coral Reef Disease
05/21/2002
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Using molecular microbiology techniques, scientists are a significant step closer to understanding and identifying the deadly microbes responsible for the mysterious black band disease that is destroying the world’s coral reef ecosystems.
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| Caenorhabditis elegans: Plague Bacteria Biofilm Blocks Food Intake
05/16/2002
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Nature 16 May 2002 Linked with permission, 05/21/02
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| Scientists Discuss Microbial Pathogenesis in Era of Bioterrorism, Drug Resistance
04/21/2002
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This American Society for Investigative Pathology symposium on “hot topics in microbial pathogenesis” provides a look into five cutting edge approaches to how pathogens get into the cell and cause their damage and what science can do about it, identifying better drug targets, even using the microbes themselves as weapons.
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| Lung Bacteria Morph into Lethal Form
04/18/2002
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Nature 18 April 2002 Linked with permission, 05/03/02
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| Coffee Stops the Rot
04/18/2002
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Nature 05 April 2002 Linked with permission, 04/16/02
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| Purdue To Help NASA Create Life-Supporting Ecosystem In Space
03/13/2002
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The National Aeronautics and Space Administration announced today (Tuesday, 3/12) that Purdue University will head a center to develop "advanced life support" technologies for sustaining human colonies on Mars and elsewhere in space.
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| Coffee May Help Prevent Cavities
03/06/2002
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A new research study indicates that coffee might help prevent cavities. The finding is reported in the Feb. 27 print issue of the Journal of Agricultural and Food Chemistry, a peer-reviewed publication of the American Chemical Society, the world’s largest scientific society.
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| Biofilm Glue Revealed
02/21/2002
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by Caroline Seydel ScienceNOW 21 Feb 2002; 221:2 Linked with permission, 02/22/02
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| New Study Confirms Periodontal Disease Linked to Heart Disease
02/21/2002
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Data Reveals Diseased Gums Pump High Levels of Harmful Bacterial Components Into Bloodstream
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| How Bacteria Stick Together
02/06/2002
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by Mary Beckman ScienceNOW 6 Feb 2002; 206:1 Linked with permission, 02/22/02
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| Switch Makes Salmonella Stick or Twist
02/06/2002
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Nature 06 February 2002 Linked with permission, 02/19/02
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| Discovery of Bacterial 'Touch Sensor' Could Lead to Biofilm Treatments
02/05/2002
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A discovery by Princeton scientists could lead to new ways to combat biofilms -- tough coatings of bacteria that form on everything from teeth and prosthetic devices to the hulls of ships.
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| Seaweed Inspires Antibacterial
01/11/2002
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Nature 11 January 2002 Linked with permission, 02/07/02
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| Study Suggests Way to Short-Circuit Microbe Communication
01/02/2002
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Scientists have learned that bacteria use an integrated communications system to sense, retrieve and process the chemical signals they depend on to find nutrients or flee from danger.
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| Paula Watnick Wins ICAAC Young Investigator Award
12/18/2001
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Paula Watnick, M.D., Ph.D., Assistant Professor, Tufts University School of Medicine and New England Medical Center, Boston, MA, will receive the ICAAC Young Investigator Award from the American Society for Microbiology.
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| Experts Announce Global Antimicrobial Resistance Initiative
12/17/2001
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World preview of the Global White Paper on bacterial resistance in respiratory tract infections - A call for concerted international action
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| Battling the Barnacle
12/17/2001
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Dr. Paul Armistead, manager of ONR’s Polymer Chemistry program is looking for ideas to outwit the offensive critters
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| Bacteria's Natural Foe Fights Drug-Resistant Infections
12/06/2001
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Scientists have turned to nature once again for help in fighting deadly infections. Reporting in the Dec. 7 issue of Science, Rockefeller University researchers show that a natural enzyme derived from tiny viruses that live inside bacteria can successfully target and kill disease bacteria, including those that are resistant to drugs.
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| New Biofilm Research Center to Explore the Wonderful World of Slime
11/28/2001
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This week, members of the Stanford faculty announced the official opening of the Biofilm Research Center. The new facility includes a $350,000 Zeiss confocal laser-scanning microscope that will allow researchers, on and off campus, to investigate the intricate world of slime.
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| New Theory Proposed for Cystic Fibrosis Infections
11/19/2001
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Cystic fibrosis (CF) is a fatal lung disease caused by an altered gene, but how the gene affects cells is not completely understood. Now, researchers have new evidence suggesting the gene can change the internal chemistry of some lung cells, making them more susceptible to certain bacteria that cause sickness and, ultimately, death.
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| Chemical Pollution and Human Sewage Could Be Killing Corals
11/06/2001
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A combination of human sewage and shipyard discharge may be responsible for the development and spread of deadly black band disease in corals, researchers at the University of Illinois say.
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| UI Researchers and Colleagues Identify Genetic Changes in Bacterial Biofilms
10/24/2001
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Using a technology known as microarray analysis, University of Iowa researchers and their collaborators at Harvard University, Northwestern University and the University of Washington, Seattle, have identified a subset of genes in a bacterium that behave differently when the organism exists as a biofilm.
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| Legionnaire's Bug Shouldn't Be Able to Infect Humans
09/19/2001
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The common water-borne bug that causes Legionnaire’s disease should not be able to infect people, according to Bath University researchers speaking today at the bi-annual meeting of the Society for General Microbiology at the University of East Anglia, UK.
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| Look! No Fillings - Perfect Teeth Without the Trauma of Frequent Trips to the Dentist
09/12/2001
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Toothache and fillings could soon be a thing of the past. On both sides of the Atlantic, scientists are developing vaccines aimed at eliminating dental caries, one of the most common infectious diseases.
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| Study: Nitric Oxide-Releasing Materials Might Reduce Medical Implant Infections
09/07/2001
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Led by Dr. Mark H. Schoenfisch, assistant professor of chemistry, researchers have found they can store nitric oxide in sol-gel based materials that could be used to coat implants. Nitric oxide, a natural anti-bacterial agent, is slowly released by the coating when placed in watery environments such as blood or tissue and reduces bacteria’s tendency stick to the implants and form living films that lead to infection.
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| Dentists Abuzz over Cavity-Prevention Potential of Honeybee Product
08/29/2001
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Dentists from the University of Rochester Medical Center and food scientists at State University of Campinas in Brazil have discovered that a substance that Brazilian honeybees make to protect their hives might prove to be a potent anti-cavity agent.
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| TIGR Completes Study Providing Insight into Infectious Strain of Bacterium that Causes Otitis, Pneumonia and Meningitis
07/19/2001
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Investigators at The Institute for Genomic Research (TIGR) today announced that they have determined the complete genome sequence of a virulent isolate (a very infectious strain) of Streptococcus pneumoniae or pneumococcus, the bacterium which causes over 3 million children and even more elderly people to die every year from pneumonia or meningitis. It is also the most common cause of otitis media or ear infection.
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| As People’s Taste for Exotic Foods Increases, So Too Does Health Risk
07/02/2001
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Food-borne pathogens long considered rare on North American plates are an emerging problem, and restaurant and home chefs should be more diligent about washing their fresh produce, University of Illinois food scientists say.
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| Report Evaluates Microbial Threats to Water Quality
06/27/2001
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New molecular techniques and recent advances in the science of microbiology can make the detection of harmful microorganisms and contaminated water faster and more accurate than ever, a new report from the American Academy of Microbiology says.
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| Researchers Uncover a Protein Defect that Causes a Milder Form of Cystic Fibrosis
06/26/2001
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Scientists at The Hospital for Sick Children have uncovered a protein defect that underlies a milder form of cystic fibrosis.
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| Treatment with Bacteria Can Protect Children from Recurrent Ear Infections
06/25/2001
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Effect of recolonisation with "interfering" alpha-streptococci on recurrences of acute and secretory otitis media in children: randomised placebo controlled trial
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| People with Rheumatoid Arthritis Have More Periodontal Disease
06/21/2001
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Swollen joints and missing teeth often go hand in hand, according to a new study in the Journal of Periodontology.
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| Scientists Sequence Genome of Major Periodontal Disease Bacterium
06/12/2001
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Scientists have sequenced the genome of Porphyromonas gingivalis, a bacterium believed to play a major role in adult periodontitis, or gum disease. It is the first oral disease-causing microbe to be completely sequenced.
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| Typhoid Mary's Gallstones to Blame
05/24/2001
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Nature 24 May 2001 Linked with permission, 10/19/01
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| Tea Fights Cavities, Reduces Plaque
05/22/2001
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Drinking tea may help fight cavities. A group of researchers from the University of Illinois College of Dentistry believe that black tea and its components benefit oral health by interfering with the harmful plaque bacteria in the mouth that cause gum disease and cavities.
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| When Shewanella Meets Goethite: Evidence Found of Recognition Between Animate and Inanimate Objects
05/17/2001
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Virginia Tech graduate student has invented a technique called biological force microscopy and he and his major professor have used it to determine what happens when Shewanella, a microorganism found in most soils, meets goethite, the most important iron oxide in soils worldwide. The research provides some of the first evidence of recognition between a living organism and an inanimate object such as a mineral.
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| UB Oral Biologists Demonstrate Gene Transfer Between Unrelated Oral Bacteria
03/09/2001
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Oral bacteria can exchange genes, raising the possibility that organisms in the oral cavity can be transformed from harmless to destructive, and from antibiotic-susceptible to antibiotic-resistant, oral biologists at the University at Buffalo School of Dental Medicine have found.
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| Human Gut Potential Breeding Ground for Antibiotic Resistance
02/16/2001
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Bacteria in your gut could be exchanging genetic material, including antibiotic resistance genes, with bacteria that are simply passing through on your food, say researchers from the University of Illinois.
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| Microbial Activity Key Component of Global Environmental Change
02/12/2001
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Managing microbial activity can play a significant role in slowing adverse effects of greenhouse gases and other global environmental changes, according to a new report from the American Society for Microbiology (ASM).
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| Dangerous Beauty: Fungal Flowers Offer Clues to Biofilm Formation on Medical Implants
01/31/2001
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A florid fungus can be a dangerous beauty, able to coat medical implants with thin films causing serious complications in patients with hip and valve replacements.
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| Scientist Searches Yellowstone Park for Carbon Dioxide-Eating Microbe
01/26/2001
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A three-member team is looking for ways of naturally lowering carbon dioxide emissions from coal-fired power plants.
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| Antibiotics, Animals, and People--Again!
01/19/2001
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Science Jan 2001; 291(5503):397 Linked with permission, 05/08/01
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| Tipsheet: Journals of the American Society
01/11/2001
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Garlic may be good for your health, but it appears that garlic powder works better than garlic oil in fighting bacteria according to researchers from the United Kingdom.
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| Cell Stickiness Behind Bozeman Biotech Firm
12/30/2000
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Cells have molecules on their surfaces that stick like Velcro to a corresponding molecule on another cell.
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| Sushi Condiment May Prevent Cavities
12/14/2000
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Wasabi, the pungent green horseradish served with Japanese sushi, has been found to afford yet another health benefit: it could prevent tooth decay.
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| Huge New Hydrothermal Vent System Found on Seafloor
12/11/2000
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A new hydrothermal vent field, which scientists have dubbed "The Lost City," was discovered December 5th on an undersea mountain in the Atlantic Ocean.
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| MIT Develops Filters for Wastewater Treatment, More
12/07/2000
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Professor Mayes' novel idea was to mix into the bulk membrane polymer solution a "comb" polymer composed of a hydrophobic backbone lined with short hydrophilic, or water-loving, "bristles."
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| Microbes Make Mine-Waste Drinkable, Science Researchers Report
11/30/2000
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Tiny bacteria that usher dissolved zinc into a solid form may help make the removal of mining waste more efficient in groundwater and wetlands
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| Discovery May Jump-Start Mine Remediation Efforts
11/29/2000
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Probing the microscopic life found in the submerged recesses of an abandoned Wisconsin lead and zinc mine, scientists have found compelling evidence that microorganisms play a key role in the formation of mineral deposits.
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| Gum Disease Higher in Heart Attack Patients
11/12/2000
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Individuals who are having a heart attack are more likely to have serious inflammation of gum tissue known as periodontal disease than those with no known heart disease
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| Study Finds Doctors often Unaware that Hospital Patients have Urinary Catheters
10/13/2000
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Doctors in the study weren't sure of patients' catheter status more than a quarter of the time. And, perhaps as a result, the researchers found that nearly one-third of patients using catheters didn't need them - putting them in needless discomfort and at unnecessary risk for urinary tract infections.
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| UI Researchers Develop Test Indicating Cystic Fibrosis Lungs are Infected with Bacterial Biofilms
10/11/2000
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A laboratory test developed by University of Iowa researchers indicates that the lungs of cystic fibrosis (CF) patients are infected primarily with bacterial biofilms, organized communities of bacterial cells that are extremely resistant to antibiotic treatment.
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| UI Researchers Find that a Simple Sugar May Prevent Lung Infections in CF Patients
10/09/2000
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The lungs contain substances that kill inhaled and aspirated bacteria, thereby preventing lung infections. This system may be disrupted in people with cystic fibrosis (CF)
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| Silver-Coated Catheters Cut Infections
09/24/2000
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University of Michigan analysis suggests that there may be a way to cut catheter-related problems in half. Silver-coated catheters, the study indicates, could reduce patients' pain, suffering and hospital time, while cutting costs for hospitals and insurers.
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| No Apparent Connection Between Periodontal Disease and Coronary Heart Disease
09/19/2000
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A thorough study suggests there is little or no connection between periodontal disease and risk of coronary heart disease, according to researchers at the University of Washington School of Dentistry
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| Day Care Centers Incubate and Spread Antibiotic-Resistant Bacteria
09/16/2000
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Day care centers act as microenvironments that facilitate and promote selection, spread and transmission of antibiotic-resistant respiratory tract organisms in the community and should be seen as major targets for intervention
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| Proposed Rule for Unregulated Contaminant Monitoring Regulation for Public Water Systems; Analytical Methods for List 2 Contaminants and Clarifications
09/13/2000
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The Safe Drinking Water Act (SDWA), as amended in 1996, requires the U.S. Environmental Protection Agency to establish criteria for a program to monitor unregulated contaminants and to publish a list of contaminants to be monitored.
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| OHSU Researchers Review How Bacteria Crawl on Surfaces
09/07/2000
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Research conducted at Oregon Health Sciences University shows how these microbes use threadlike protein filaments to manuever themselves into position.
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| Deadly for Bacteria, Great for Consumers Electrolyzed Water Rivals Chlorine and Heat for Killing E. coli, Salmonella and Listeria
08/24/2000
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Electricity and water can be fatal. But that could be good news for consumers now that researchers have shown the deadly combination also kills bacteria like E. coli, salmonella and listeria on foods and food utensils.
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| Molecular-Scale Roughness Identified as Factor in Bacteria's Ability to Stick to Surfaces
08/22/2000
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Using an atomic force microscope to probe the surface of glass, mica, and quartz at the molecular level, Penn State engineers have, for the first time, identified the bacteria-sized peaks and valleys in this tiny terrain as an important factor in microbes's ability to adhere to some of these materials.
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| Biofilms in Urinary and Foley Catheters
08/10/2000
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Model Bladder for Foley Catheter Testing This model enables growth of bacterial biofilms in foley catheters for gene transfer and other experiments.
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| Study at Rush-Presbyterian-St. Luke Medical Center Reports Short-term Benefit in Treating Autism with Antibiotic Agent
07/18/2000
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Researchers at Rush-Presbyterian-St. Luke's Medical Center in Chicago have shown that some children suffering from autism may experience short-term but dramatic improvement during treatment with appropriate antibiotics.
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| Misuse of Antibiotics Fueled by Culture and Economics
07/17/2000
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Current patterns of antibiotic use reflect cultural and economic forces as much as clinical need
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| How E. coli Bacteria Put a Death Grip on Intestinal Cells
06/29/2000
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A team of molecular biologists and x-ray crystallographers has produced the first detailed picture showing how pathogenic E. coli bacteria achieve a molecular death grip on intestinal cells.
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| AMA Urges Regulation of Antibacterial Household Products
06/15/2000
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Acting on growing concern about the proliferation of antibiotic-resistant germs, the American Medical Association Wednesday urged increased government regulation of antibacterial soaps, cleaners, lotions and other household products.
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| Carbon Diem: Grants Awarded to Research that Seizes Excess Carbon Dioxide
05/15/2000
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Researchers interested in tidying up the earth's atmosphere are devising ways to sweep up excess carbon dioxide -- a potentially problematic greenhouse gas -- and store it out of harm's way.
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| Proposed Rule for Groundwater Systems
05/10/2000
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EPA is proposing to require a targeted risk-based regulatory strategy for all ground water systems.
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| Slow-Release Antibiotic on Device Surfaces Shows Promise Against Infections
05/01/2000
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A University of Washington bioengineer led a team that has created a ciprofloxacin- containing polymer that releases antibiotic slowly onto the surface of hospital devices, such as catheters and prostheses, to reduce the risk of biofilm-related infections.
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| Microbial Ecology of Biofilms in Beef Processing Facilities
04/10/2000
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Researchers at the University of Guelph are working to improve their understanding of microbial pathogens in beef, prevent their passage into the food chain and support the development of new processes which improve the quality of beef.
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| Bioreactor Serves as Mini Treatment Plant
04/01/2000
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A German researcher has developed a water treatment reactor that serves as a minibiological purification plant for servicing a single home or a few households.
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| Initiative for Future Agriculture and Food Systems (RFP)
03/06/2000
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Department of Agriculture Cooperative State Research, Education, and Extension Service Request for Proposals (RFP): Initiative for Future Agriculture and Food Systems, FY 2000; Notice
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| UF Dental Researcher Develops Genetically Altered Bacteria Strain That May Fight Cavities for a Lifetime
02/08/2000
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Fighting tooth decay could someday be as simple as using a mouth rinse, thanks to a University of Florida researcher who has genetically altered the bacterium known to cause tooth decay into a form that may permanently prevent the disease.
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| FDA Clears Endoluminal Brush to Help Detect Infection Source
02/03/2000
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The FDA has cleared FAS INTERNATIONAL LTD.'s (Calgary, Alberta) endoluminal brush, which will be launched in the spring, the company announced Wednesday.
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