EPA Contracts $1.7 Million to Support Test Method Development for Antimicrobial Products
On April 1, 2008, the MSU-Center for Biofilm Engineering Standardized Biofilm Methods
Laboratory was awarded a 5 year, $1.7 million contract with the U.S. Environmental
Protection Agency (EPA).Work performed under this contract will include laboratory
research to support the development and standardization of test methods for measuring
the performance of antimicrobial products, including those for biofilm bacteria, and
statistical services related to EPA's Office of Pesticide Programs Antimicrobial Testing
Program and various Homeland Security initiatives. Darla Goeres is the contract's
principal investigator and Marty Hamilton of Big Sky Statistical Analysts LLC will
collaborate on the project as a statistical subcontractor.
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New Employment
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Engineering Associate – CMC Development
Sr. Research Scientist/ Director: Formulation Development
Sr. Research Scientist/Director: Pre-clinical Studies
Research Associate II: Biopharmaceutical Analysis
LigoCyte Pharmaceuticals, Inc
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New Patents
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7,367,346 : Method for cleaning hollow tubing and fibers
7,365,184 : B. anthracis prevention and treatment: mutant B. anthracis lacking luxS activity and furanone inhibition of growth, AI-2 quorum sensing, and toxin production
7,354,900 : Treatment and inhibition of ocular infections and wounds by CAP37 and CAP37 peptides
7,348,420 : Lactobacillus acidophilus nucleic acid sequences encoding cell surface protein homologues and uses therefore
7,347,970 : Biocides based on silanol terminated silanes and siloxanes
7,347,941 : Treating micro-organisms in water using boron conditioned enzymes and composition therefor
7,341,841 : Rapid microbial detection and antimicrobial susceptibility testing
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New Media Alert
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Accessing Uncultivated Microorganisms: From the Environment to Organisms and Genomes and Back
ASM Press
Editor: Karsten Zengler, University of California, San Diego
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New Research
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BIOTECHNOLOGY
Quorum sensing inhibitory drugs as next generation antimicrobials: Worth the effort?
Bjarnsholt T, Givskov M
Curr Infect Dis Rep Mar 2008; 10(1):22-28
PubMed Abstract
Medical biofilms
Bryers JD
Biotechnol Bioeng May 2008; 100(1):1-18
PubMed Abstract
Virtual screening for novel quorum sensing inhibitors to eradicate biofilm formation of Pseudomonas aeruginosa
Zeng Z, Qian L, Cao L, Tan H, Huang Y, Xue X, Shen Y, Zhou S
Appl Microbiol Biotechnol Mar 2008; [Epub ahead of print]
PubMed Abstract
Laser disruption of biofilm
Krespi YP, Stoodley P, Hall-Stoodley L
Laryngoscope Apr 2008;
PubMed Abstract
DENTAL
Site-specific development of periodontal disease is associated with increased levels of Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia in subgingival plaque
Mineoka T, Awano S, Rikimaru T, Kurata H, Yoshida A, Ansai T, Takehara T
J Periodontol Apr 2008; 79(4):670-676
PubMed Abstract
Biofilms in the edentulous oral cavity
Sachdeo A, Haffajee AD, Socransky SS
J Prosthodont Mar 2008;
PubMed Abstract
Use of the modified Robbins device to study the in vitro biofilm removal efficacy of NitrAdine™ a novel disinfecting formula for the maintenance of oral medical devices
Coenye T, De Prijck K, De Wever B, Nelis HJ
J Appl Microbiol Mar 2008;
PubMed Abstract
ENVIRONMENTAL
Review: Stochasticity and cell fate
Losick R, Desplan C
Science Apr 4 2008; 320(5872):65-68
Bacteria subsisting on antibiotics
Dantas G, Sommer MOA, Oluwasegun RD, Church GM
Science Apr 4 2008; 320(5872):100-103
Control of cell fate by the formation of an architecturally complex bacterial community
Vlamakis H, Aguilar C, Losick R, Kolter R
Genes Dev Apr 2008; 22(7):945-953
PubMed Abstract
Community level assessment of the effects of the broad spectrum antimicrobial chlorhexidine on the outcome of river microbial biofilm development
Lawrence JR, Zhu B, Swerhone GD, Topp E, Roy J, Wassenaar LI, Rema T, Korber DR
Appl Environ Microbiol Mar 2008;
PubMed Abstract
Cloth colorization caused by microbial biofilm
Tsuchiya Y, Ohta J, Ishida Y, Morisaki H
Colloids Surf B Biointerfaces Feb 2008;
PubMed Abstract
Causes and consequences of plant-associated biofilms
Rudrappa T, Biedrzycki ML, Bais HP
FEMS Microbiol Ecol Mar 2008;
PubMed Abstract
Impact of nitrate on structure and function of bacterial biofilm communities in pipelines for seawater injection into oilfields
Schwermer CU, Lavik G, Abed RM, Dunsmore B, Ferdelman TG, Stoodley P, Gieseke A, de Beer D
Appl Environ Microbiol May 2008;
PubMed Abstract
Characterization of an Helicobacter pylori environmental strain
Cellini L, Grande R, Di Campli E, Di Bartolomeo S, Di Giulio M, Traini T, Trubiani O
J Appl Microbiol Apr 2008;
PubMed Abstract
Chloraminated drinking water does not generate bacterial resistance to antibiotics in Pseudomonas aeruginosa biofilms
Jurgens DJ, Sattar SA, Mah TF
Lett Appl Microbiol May 2008; 46(5):562-567
PubMed Abstract
Dynamics of Legionella spp and bacterial populations during the proliferation of l pneumophila in a cooling tower facility
Wery N, Bru-Adan V, Minervini C, Delgenes JP, Garrelly L, Godon JJ
Appl Environ Microbiol Apr 2008;
PubMed Abstract
FOOD
Effect of food preservatives on in situ biofilm formation
Arweiler NB, Lenz R, Sculean A, Al-Ahmad A, Hellwig E, Auschill TM
Clin Oral Investig Mar 2008;
PubMed Abstract
Temperature and nutrient effects on Campylobacter jejuni attachment on multispecies biofilms on stainless steel
Sanders SQ, Frank JF, Arnold JW
J Food Prot Feb 2008;71(2):271-278
PubMed Abstract
Effects of commonly used food preservatives on biofilm formation of Streptococcus mutans in vitro
Al-Ahmad A, Wiedmann-Al-Ahmad M, Auschill TM, Follo M, Braun G, Hellwig E, Arweiler NB
Arch Oral Biol Apr 2008;
PubMed Abstract
MEDICAL
Pathogenesis of mucosal biofilm infections: Challenges and progress
Dongari-Bagtzoglou A
Expert Rev Anti Infect Ther Apr 2008; 6(2):201-208
PubMed Abstract
Mucosal biofilms: Challenges and future directions
Dongari-Bagtzoglou A
Expert Rev Anti Infect Ther Apr 2008; 6(2):141-144
PubMed Abstract
Occurrence of fungi in water used at a haemodialysis centre
Pires-Goncalves RH, Sartori FG, Montanari LB, Zaia JE, Melhem MS, Mendes-Giannini MJ, Martins CH
Lett Appl Microbiol Mar 2008;
PubMed Abstract
Identification of microbial biofilms in osteonecrosis of the jaws secondary to bisphosphonate therapy
Sedghizadeh PP, Kumar SK, Gorur A, Schaudinn C, Shuler CF, Costerton JW
J Oral Maxillofac Surg Apr 2008; 66(4):767-775
PubMed Abstract
Metal-on-metal bearings in total hip arthroplasties: Influence of cobalt and chromium ions on bacterial growth and biofilm formation
Hosman AH, van der Mei HC, Bulstra SK, Busscher HJ, Neut D
J Biomed Mater Res A Mar 2008; [Epub ahead of print]
PubMed Abstract
Antimicrobial-coated endotracheal tubes: An experimental study
Berra L, Curto F, Li Bassi G, Laquerriere P, Pitts B, Baccarelli A, Kolobow T
Intensive Care Med Apr 2008;
PubMed Abstract
Internally coated endotracheal tubes with silver sulfadiazine in polyurethane to prevent bacterial colonization: A clinical trial
Berra L, Kolobow T, Laquerriere P, Pitts B, Bramati S, Pohlmann J, Marelli C, Panzeri M,
Brambillasca P, Villa F, Baccarelli A, Bouthors S, Stelfox HT, Bigatello LM, Moss J,
Pesenti A
Intensive Care Med Apr 2008; PubMed Abstract
In vitro activity of anidulafungin against Candida albicans biofilms
Jacobson MJ, Piper KE, Nguyen G, Steckelberg JM, Patel R
Antimicrob Agents Chemother Apr 2008;
PubMed Abstract
Identification of Streptococcus sanguinis genes required for biofilm formation and examination of their role in endocarditis virulence
Ge X, Kitten T, Chen Z, Lee SP, Munro CL, Xu P
Infect Immun Apr 2008;
PubMed Abstract
Opr86 is essential for viability and is a potential Candidate for a protective antigen against biofilm formation by Pseudomonas aeruginosa
Tashiro Y, Nomura N, Nakao R, Senpuku H, Kariyama R, Kumon H, Kosono S, Watanabe H, Nakajima T, Uchiyama H
J Bacteriol Apr 2008;
PubMed Abstract
METHODS
Microbe repelling coated stainless steel analysed by field emission scanning electron microscopy and physicochemical methods
Raulio M, Jarn M, Ahola J, Peltonen J, Rosenholm JB, Tervakangas S, Kolehmainen J, Ruokolainen T, Narko P, Salkinoja-Salonen M
J Ind Microbiol Biotechnol Apr 2008;
PubMed Abstract
Analysis of microbial extracellular polysaccharides in biofilms by hplc part i: Development of the analytical method using two complementary stationary phases
Meisen S, Wingender J, Telgheder U
Anal Bioanal Chem Apr 2008;
PubMed Abstract
New method showing the influence of matrix components in Leuconostoc mesenteroides biofilm formation
Badel S, Laroche C, Gardarin C, Bernardi T, Michaud P
Appl Biochem Biotechnol Apr 2008;
PubMed Abstract
Quantification of lipids and protein in thin biofilms by fluorescence staining
Larsen P, Olesen BH, Nielsen PH, Nielsen JL
Biofouling2008; 24(4):241-250
PubMed Abstract
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Biofilm Engineering
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University-Bozeman